oral drug delivery provides an excellent route of drug delivery
into systemic circulation. It has inherent advantages such as prompt
onset of action & predictable drug delivery.
Pain (BTP) occurs once or more times a day to terminally ill cancer
patients and severely compromises their quality of life. The need
of the hour is a drug delivery that provides prompt and potent onset
of action for each episode of BTP.
OTFC, is a lozenge of Fentanyl Citrate for the treatment of breakthrough
pain. As soon as the patient rolls the lozenge in his/her oral cavity,
the drug released from the lozenge gets absorbed from the oral mucosa
. The pain relief starts in about 10-12 minutes and lasts for 20-25
minutes. In the event the patient experiences any adverse effects,
he/she can simply take the lozenge out and the effect will wear
off in a few minutes.
are several other products manufactured using proprietary Intra
Oral drug delivery technology viz. nitroglycerine, short acting
benzodiazepines, an NSAID etc.